Compound Q&A

How is m-PEG3-CH2CH2COOH (CAS: 67319-28-2) typically synthesized?

Answer

m-PEG3-CH2CH2COOH
m-PEG3-CH2CH2COOH is synthesized through the modification of polyethylene glycol (PEG) using a coupling reagent such as N-hydroxysuccinimide (NHS) ester. The reaction involves the NHS ester reacting with the carboxylic acid group of the PEG, followed by the addition of a coupling agent to form the amide bond. This process yields a high-selectivity product with good yield.

About

CAS No 67319-28-2
English Name m-PEG3-CH2CH2COOH
Molecular Formula C10H20O6
Molecular Weight 236.26 g/mol
SMILES COCCOCCOCCOCCC(=O)O
InChIKey ZMCJTXKSDDFJRG-UHFFFAOYSA-N
Last Updated: 2025-10-13 12:55

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