2-{3-[(7-{3-[Ethyl(2-hydroxyethyl)amino]propoxy}-4-quinazolinyl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide(CAS: 722544-51-6)
![2-{3-[(7-{3-[Ethyl(2-hydroxyethyl)amino]propoxy}-4-quinazolinyl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide 2-{3-[(7-{3-[Ethyl(2-hydroxyethyl)amino]propoxy}-4-quinazolinyl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide](https://static.chemtradehub.com/structs/722/722544-51-6-413d.webp)
CAS Number
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Basic Information
Molecular Formula
C26H30FN7O3
Molecular Weight
507.57 g/mol
Physical Properties
Boiling Point
796.7±60.0°C at 760 mmHg
Density
1.359
Flash Point
435.6°C
Chemical Identifiers
SMILES
CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO
InChIKey
QYZOGCMHVIGURT-UHFFFAOYSA-N
Database References
MDL Number
MFCD10687152
FAQ
The compound has a crystalline form and a molecular weight of approximately 660.45 g/mol. It is slightly soluble in water and has good solubility in organic solvents like methanol and ethanol. The compound is reactive towards nucleophiles and is stable under neutral and slightly acidic conditions. It does not exhibit significant volatility or flammability.
The compound is synthesized via a multi-step process involving the reaction of a quinazoline derivative with an amine and pyrazole. The synthesis typically uses catalytic amounts of a base like potassium carbonate and is carried out under mild conditions. The yield is around 75%, and the product is isolated by recrystallization from ethanol.
This compound is primarily used in the pharmaceutical industry due to its potential as a drug candidate. It may also be used in the development of sensors and as an intermediate in the synthesis of other organic compounds. Specific applications in semiconductors and polymers are less common but possible depending on its functional groups.
When handling this compound, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood due to its reactivity. Spills should be cleaned up with caution using absorbent materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
Contact Person
Aladdin
market@aladdin-e.com







![Hydrogen [hydroxy(oxo)silyl]silicate](https://static.chemtradehub.com/structs/148/14808-60-7-ed6a.webp)


![2-{3-[(7-{3-[Ethyl(2-hydroxyethyl)amino]propoxy}-4-quinazolinyl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide — ShangHaiYiJiShengWuKeJiYouXianGongSiXiaoShouBu](https://static.chemtradehub.com/suppliers/67cecfe92b2de6e8e95a656d/67cecfe92b2de6e8e95a656d-logo.webp)
![2-{3-[(7-{3-[Ethyl(2-hydroxyethyl)amino]propoxy}-4-quinazolinyl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide — ShangHaiJiZhiShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67cecbee2b2de6e8e95a5b72/67cecbee2b2de6e8e95a5b72-logo.webp)
![2-{3-[(7-{3-[Ethyl(2-hydroxyethyl)amino]propoxy}-4-quinazolinyl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide — Hubei Nona Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce946e2b2de6e8e95a4840/67ce946e2b2de6e8e95a4840-logo.webp)
![2-{3-[(7-{3-[Ethyl(2-hydroxyethyl)amino]propoxy}-4-quinazolinyl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide — ShangHaiMaiRuiErShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67ced3b52b2de6e8e95a6e52/67ced3b52b2de6e8e95a6e52-logo.webp)
![2-{3-[(7-{3-[Ethyl(2-hydroxyethyl)amino]propoxy}-4-quinazolinyl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide — MedChemExpress LLC](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fd/67ced0fb2b2de6e8e95a67fd-logo.webp)