4,6-Dichloronicotinamide(CAS: 70593-57-6)

4,6-Dichloronicotinamide is a solid compound with a crystalline form. Its molecular weight is approximately 219.01 g/mol. It is slightly soluble in water and ethanol. Chemically, it is less reactive, but it can undergo substitution reactions. It has a melting point of around 180-182°C and a boiling point of about 300°C. It is not flammable but can react with strong reducing agents.

4,6-Dichloronicotinamide is typically synthesized by the reaction of 3,5-dichloropyridine with anhydrous ammonia. The reaction yields the target compound in good yield. The process requires mild conditions, and the use of a suitable catalyst may enhance the reaction efficiency. The product is usually purified by recrystallization from water or ethanol.

4,6-Dichloronicotinamide finds applications in various industries. It is used as a precursor in the synthesis of pharmaceuticals and organic dyes. It also has potential in the polymer industry for the production of certain polymers and in the development of sensors and semiconductors due to its unique chemical properties.

When handling 4,6-Dichloronicotinamide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spill, it should be cleaned up with care to avoid skin contact. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.