(3R)-3-Pyrrolidinamine dihydrochloride(CAS: 116183-81-4)

(3R)-3-Pyrrolidinamine dihydrochloride is a white to off-white crystalline powder. Its molecular weight is approximately 226.74 g/mol. It is soluble in water and ethanol. It is highly reactive and undergoes hydrolysis in aqueous solutions.

(3R)-3-Pyrrolidinamine dihydrochloride is usually synthesized through the reaction of 3-pyrrolidinamine with hydrochloric acid. Common methods include microscale synthesis using a Dean-Stark apparatus to remove water and ensure high yield. The reaction is carried out under mild conditions to maintain the desired stereochemistry.

(3R)-3-Pyrrolidinamine dihydrochloride is primarily used in the pharmaceutical industry as a precursor for drug synthesis. It is also found in some polymer formulations, particularly as a stabilizer. Additionally, it has applications in sensor technology and semiconductor manufacturing as a dopant.

When handling (3R)-3-Pyrrolidinamine dihydrochloride, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and lab coats. This compound should be stored in a well-ventilated area and away from heat sources. In case of a spill, ensure the area is properly ventilated and use appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.