5'-O-DMT-2'-O-iBu-N-Bz-Guanosine(CAS: 81279-39-2)

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine is a crystalline compound with a molecular weight of approximately 615.48 g/mol. It has low water solubility and moderate solubility in organic solvents. This compound is relatively stable under acidic and basic conditions, but can react with nucleophiles. It is often used for its fluorescent properties and is found in various chemical and pharmaceutical applications.

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine is typically synthesized through a multi-step process involving coupling of guanosine with DMT (N,N'-Diisopropylcarbodiimide) and Boc (tert-butoxycarbonyl) protecting groups. The synthesis involves protecting the hydroxyl groups and then installing the desired functionalities, followed by deprotection to obtain the final product. This process requires careful selection of reagents and conditions to achieve high yield and selectivity.

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine finds application in multiple industries, particularly in pharmaceuticals, where it serves as a fluorescence probe and for the development of therapeutic agents. It is also used in polymer science for functionalizing materials and in biosensors for detecting nucleic acids.

When handling 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine, it is essential to use appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be immediately cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed information on handling and disposal.