4-Acetamido-2-aminobenzenesulfonic acid(CAS: 88-64-2)

4-Acetamido-2-aminobenzenesulfonic acid is a white crystalline solid with a molecular weight of approximately 250.24 g/mol. It has a solubility of about 3.6 g/L in water at 25°C. Chemically, it is highly reactive, particularly in acidic or basic conditions, and can undergo various reactions such as esterification and sulfonation.

4-Acetamido-2-aminobenzenesulfonic acid is typically synthesized via the sulfonation of 4-acetamido-2-aminobenzenesulfonate. The reaction involves the use of fuming sulfuric acid as the sulfonating agent under heated conditions (typically 120-150°C) with careful control to achieve high selectivity and yield.

4-Acetamido-2-aminobenzenesulfonic acid is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drugs. It also finds applications in the polymer industry for improving the properties of plastics and in the electronics industry for the production of sensors and semiconductors.

When handling 4-Acetamido-2-aminobenzenesulfonic acid, it is crucial to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. In case of a spill, it should be cleaned up promptly using appropriate materials, and the area should be thoroughly rinsed with water. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal procedures.