Methyl 2-amino-5-bromoisonicotinate(CAS: 882499-87-8)

Methyl 2-amino-5-bromoisonicotinate (CAS: 882499-87-8) is a crystalline compound with a molecular weight of approximately 244.04 g/mol. It has a solubility of about 0.1 g/L in water at 20°C. It is moderately reactive, particularly with nucleophiles. The compound is stable under normal conditions but may react under basic conditions.

Methyl 2-amino-5-bromoisonicotinate (CAS: 882499-87-8) is typically synthesized by bromination of methyl nicotinate followed by amidation. Common reagents include N-bromosuccinimide (NBS) and triphenylphosphine as a catalyst. The yield is moderate, and the selectivity is good.

Methyl 2-amino-5-bromoisonicotinate (CAS: 882499-87-8) is used in the pharmaceutical industry for the preparation of certain drug intermediates. It is also used in the chemical industry for the synthesis of various organic compounds and as a reagent in polymer and semiconductor applications.

When handling Methyl 2-amino-5-bromoisonicotinate (CAS: 882499-87-8), it is important to wear appropriate personal protective equipment (PPE), including gloves and goggles. Store the compound in a cool, dry place away from direct sunlight. In case of spill, handle with care and use appropriate spill kits. Always consult the Safety Data Sheet (SDS) for detailed instructions.