4-(4-Morpholinyl)aniline(CAS: 2524-67-6)

4-(4-Morpholinyl)aniline (CAS: 2524-67-6) is a white crystalline solid with a molecular weight of approximately 204.28 g/mol. It has a solubility of about 24 g/100 mL in water and is slightly soluble in ethanol. The compound is moderately reactive, particularly towards electrophilic aromatic substitution reactions. It is soluble in organic solvents like methanol and acetone. It is not flammable but may form explosive peroxides in storage.

4-(4-Morpholinyl)aniline is typically synthesized by the reaction of 4-chloroaniline with morpholine in the presence of a base such as sodium hydroxide. The process involves stirring the mixture at room temperature, followed by acidification and recrystallization to obtain the desired product. This method provides a high yield and good selectivity, with a purity of over 95%.

4-(4-Morpholinyl)aniline is used in various industries. In the pharmaceutical industry, it is a precursor for the synthesis of certain drug molecules. In the polymer industry, it can be used as a monomer for the production of polymers. Additionally, it finds applications in the manufacturing of sensors and as a reagent in semiconductor processing.

When handling 4-(4-Morpholinyl)aniline (CAS: 2524-67-6), it is essential to wear appropriate personal protective equipment (PPE) including gloves and safety glasses. It should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. Handling should be done in a well-ventilated area or fume hood to avoid inhalation of fumes. Refer to the Safety Data Sheet (SDS) for detailed safety instructions.