Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 6'-hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethyl-, (6'R)-(CAS: 158440-71-2)

This compound is a crystalline solid with a molecular weight of approximately 268.39 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetone. Chemically, it is reactive towards nucleophiles and can undergo various transformations such as esterification and reduction. It features a spiro cyclopropane ring fused to an indene ring with hydroxyl and hydroxymethyl substituents.

The compound is often synthesized via a multistep process involving the formation of the spiro cyclopropane ring, followed by selective introduction of hydroxyl, hydroxymethyl, and alkyl substituents. Common synthetic methods include reactions with epoxides, Grignard reagents, and various protecting groups. Efficient catalysts and selectivity are crucial for achieving the desired product with high yield.

This compound is used in the pharmaceutical industry for the development of new drugs due to its unique chemical structure. It also finds applications in the synthesis of certain types of polymers and as a component in sensors where its reactive properties can be exploited. Additionally, it may be used in the semiconductor industry for specific chemical processes.

When handling this compound, it is essential to use proper personal protective equipment (PPE) such as gloves and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to potential vapors. Spills should be managed according to standard procedures, and the Safety Data Sheet (SDS) should be consulted for specific disposal and emergency response guidelines.