(2S)-2-amino-3-(4-cyanophenyl)propanoic acid(CAS: 167479-78-9)

(2S)-2-Amino-3-(4-cyanophenyl)propanoic acid is a white crystalline solid with a molecular weight of approximately 224.13 g/mol. It is soluble in water and has moderate solubility in organic solvents. The compound is known for its reactivity in amide formation and nucleophilic substitution reactions.

(2S)-2-Amino-3-(4-cyanophenyl)propanoic acid can be synthesized through a multistep process involving the reaction of a 4-cyanophenyl substituted compound with an amine. Common methods include Grignard reagent addition followed by acidification, or direct coupling of a 4-cyanophenyl group with an amino acid. The yield and selectivity can be controlled by choosing appropriate catalysts and reaction conditions.

(2S)-2-Amino-3-(4-cyanophenyl)propanoic acid finds application in the pharmaceutical industry for developing new drug candidates. It is also utilized in the production of polymers, sensors, and as a building block in the synthesis of semiconductors. Its unique chemical properties make it valuable in these diverse sectors.

When handling (2S)-2-amino-3-(4-cyanophenyl)propanoic acid, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be contained and disposed of according to local regulations. For detailed safety information, refer to the Material Safety Data Sheet (MSDS).