3-Bromo-4-(1H-imidazol-1-yl)benzaldehyde(CAS: 861932-08-3)

3-Bromo-4-(1H-imidazol-1-yl)benzaldehyde (CAS: 861932-08-3) is a crystalline solid with a molecular weight of approximately 252.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dichloromethane. This compound is known for its reactivity, particularly in nucleophilic substitution reactions at the bromine atom and condensation reactions involving the benzaldehyde moiety. It is used in various synthetic routes and as a building block in organic synthesis.

3-Bromo-4-(1H-imidazol-1-yl)benzaldehyde (CAS: 861932-08-3) can be synthesized through the condensation of 4-bromoacetophenone with 1H-imidazole followed by the introduction of the benzaldehyde group. The reaction typically requires a catalyst such as sodium ethoxide in ethanol. High selectivity and good yield are achieved under these conditions, making this a popular method in academic and industrial settings.

3-Bromo-4-(1H-imidazol-1-yl)benzaldehyde (CAS: 861932-08-3) is used in the pharmaceutical industry for the synthesis of various drug candidates due to its functional groups. It is also employed in the polymer industry for developing new materials with specific properties. Additionally, it finds applications in sensor technology for its reactivity and in semiconductor manufacturing for its use in organic thin-film transistors.

When handling 3-Bromo-4-(1H-imidazol-1-yl)benzaldehyde (CAS: 861932-08-3), it is crucial to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area, preferably under a fume hood. Spills should be cleaned up using appropriate chemicals, and the area should be well-ventilated. In case of skin or eye contact, immediate washing with plenty of water and seeking medical advice is recommended. A Safety Data Sheet (SDS) should be consulted for detailed procedures and emergency information.