4-Hydroxymethyl-4'-methyl-2,2'-bipyridyl(CAS: 81998-04-1)

4-Hydroxymethyl-4'-methyl-2,2'-bipyridyl is a crystalline solid with a molecular weight of approximately 248.25 g/mol. It has limited water solubility and moderate solubility in common organic solvents. The compound has a basic nature and exhibits good stability under normal conditions. It is reactive towards electrophiles and bases, and is commonly used in chemical syntheses and as a ligand in coordination chemistry.

4-Hydroxymethyl-4'-methyl-2,2'-bipyridyl is typically synthesized through a condensation reaction of 4-hydroxymethylpyridine and 4-methylpyridine in the presence of an acid catalyst. The reaction yields a mixture of products, and the desired compound can be isolated and purified by recrystallization. The yield is generally around 70-80%, and the purity is typically 95-98%.

4-Hydroxymethyl-4'-methyl-2,2'-bipyridyl is used in various industries, including pharmaceuticals, where it serves as a ligand in coordination chemistry, and in the development of diagnostic reagents and sensors. It is also utilized in the synthesis of polymers and semiconductors, where its stability and reactivity make it a valuable compound.

When handling 4-Hydroxymethyl-4'-methyl-2,2'-bipyridyl, wear appropriate personal protective equipment (PPE) including gloves and safety goggles. Store the compound in a closed container away from heat and direct sunlight. Use a fume hood during manipulation to avoid inhalation. In case of spill, use appropriate spill clean-up materials and wash the area with water. Refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage information.