1-(2-Methoxyphenyl)piperazine hydrobromide (1:1)(CAS: 100939-96-6)

1-(2-Methoxyphenyl)piperazine hydrobromide (CAS: 100939-96-6) is a crystalline compound with a molecular weight of approximately 295.08 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dimethyl sulfoxide. Chemically, it is stable under normal conditions but should be kept away from strong acids and bases. It exhibits basic properties due to the presence of the hydrobromide salt group.

1-(2-Methoxyphenyl)piperazine hydrobromide is typically synthesized by reacting piperazine with 2-methoxybenzoyl chloride in the presence of a base like triethylamine. The reaction is carried out in an organic solvent such as dichloromethane. The product is then treated with hydrogen bromide to form the hydrobromide salt. The purity and yield can be improved by recrystallization from appropriate solvents.

1-(2-Methoxyphenyl)piperazine hydrobromide (CAS: 100939-96-6) is primarily used in pharmaceuticals for its structural similarity to other piperazine derivatives, which are often used as antipsychotics. It may also find applications in polymer synthesis, as a ligand in coordination chemistry, and in the development of sensors for detecting specific chemical compounds. Its use in semiconductors is less common due to the absence of semiconducting properties.

When handling 1-(2-Methoxyphenyl)piperazine hydrobromide (CAS: 100939-96-6), it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. The substance should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be carefully cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions. Laboratory operations involving this compound should be conducted in a well-ventilated area or fume hood to minimize exposure risks.