Compound Q&A
How is 1-(2-Methoxyphenyl)piperazine hydrobromide (CAS: 100939-96-6) typically synthesized?
Answer
1-(2-Methoxyphenyl)piperazine hydrobromide is typically synthesized by reacting piperazine with 2-methoxybenzoyl chloride in the presence of a base like triethylamine. The reaction is carried out in an organic solvent such as dichloromethane. The product is then treated with hydrogen bromide to form the hydrobromide salt. The purity and yield can be improved by recrystallization from appropriate solvents.
About
CAS No
100939-96-6
English Name
1-(2-Methoxyphenyl)piperazine hydrobromide (1:1)
Molecular Formula
C11H17BrN2O
Molecular Weight
273.1739999999999 g/mol
SMILES
COC1=CC=CC=C1N2CCNCC2.Br
InChIKey
QPAHBXFXDDEKNB-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53
