4-Bromoisoxazole(CAS: 97925-43-4)

4-Bromoisoxazole (CAS: 97925-43-4) is a crystalline solid with a molecular weight of approximately 182.02 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dichloromethane. Chemically, it shows moderate reactivity towards nucleophiles and can undergo substitution reactions. It also has applications in pharmaceuticals and organic synthesis.

4-Bromoisoxazole is typically synthesized by bromination of isoxazole. This can be achieved through direct bromination using bromine in the presence of a Lewis acid like aluminum bromide or through a nucleophilic substitution reaction using bromine and an appropriate base such as sodium hydroxide in an organic solvent. The yield and selectivity depend on the reaction conditions and catalysts used.

4-Bromoisoxazole (CAS: 97925-43-4) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It also finds applications in the polymer industry for modifying polymer properties and in the sensor technology for detecting specific compounds. Additionally, it is used in the semiconductor industry for certain photolithographic processes.

When handling 4-Bromoisoxazole (CAS: 97925-43-4), it is essential to wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure proper ventilation in the laboratory and use a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents and disposing of them according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.