1-azabicyclo[2.2.2]octan-3-amine dihydrochloride(CAS: 6530-09-2)

1-Azabicyclo[2.2.2]octan-3-amine dihydrochloride is a crystalline solid with a molecular weight of approximately 226.8 g/mol. It has a solubility of about 1.4 g/100 mL in water. This compound is moderately reactive and can form complexes with various metal ions. It is often used in organic synthesis and pharmaceutical applications.

1-Azabicyclo[2.2.2]octan-3-amine dihydrochloride is typically synthesized via a multi-step reaction involving the formation of azabicyclo[2.2.2]octane followed by amine addition and subsequent chlorination. Commonly, this involves the use of acrylonitrile and cyclopentanone as starting materials, with hydrochloric acid as the final step to form the dihydrochloride salt.

1-Azabicyclo[2.2.2]octan-3-amine dihydrochloride is used in various industries, including pharmaceuticals, where it serves as a precursor in drug synthesis, and in polymers, where it can enhance certain properties. It is also utilized in the development of sensors and semiconductors due to its unique chemical structure.

When handling 1-azabicyclo[2.2.2]octan-3-amine dihydrochloride, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to avoid inhalation. Spills should be cleaned up with appropriate absorbent materials, and the area should be well-ventilated. Always consult the safety data sheet (SDS) for detailed handling instructions.