4-Bromo-2,6-difluorophenol(CAS: 104197-13-9)

4-Bromo-2,6-difluorophenol (CAS: 104197-13-9) is a white or off-white crystalline solid with a molecular weight of approximately 231.03 g/mol. It has a low solubility in water, with a value of around 0.01 g/L at 25°C. It is not highly reactive under normal conditions, but it can undergo bromination and other substitution reactions. The compound is stable under normal storage conditions but should be protected from light and moisture.

4-Bromo-2,6-difluorophenol (CAS: 104197-13-9) is usually synthesized through a multi-step process involving bromination of 2,6-difluorophenol followed by an electrophilic aromatic substitution. The reaction typically requires a Lewis acid catalyst such as aluminum bromide (AlBr3) and is conducted in an anhydrous environment. The yield can be around 50-70%, depending on the optimization of the reaction conditions.

4-Bromo-2,6-difluorophenol (CAS: 104197-13-9) is used primarily in the pharmaceutical industry for the synthesis of certain drugs due to its unique chemical structure. It is also utilized in the polymer industry for the production of specialty polymers, in the semiconductor industry for the fabrication of electronic materials, and in sensor technology for its detection properties.

When handling 4-Bromo-2,6-difluorophenol (CAS: 104197-13-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a fume hood to minimize exposure to vapors. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and storage information.