Ethyl 1-iodoethyl carbonate(CAS: 80196-04-9)

Ethyl 1-iodoethyl carbonate (CAS: 80196-04-9) is a white crystalline solid with a molecular weight of approximately 279.01 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity towards nucleophiles, particularly amines and alcohols, making it valuable in organic synthesis.

Ethyl 1-iodoethyl carbonate (CAS: 80196-04-9) is synthesized via the reaction of ethyl carbonate with iodine in the presence of a Lewis acid catalyst, such as aluminum trichloride. The reaction proceeds to high yield, and the product is purified by recrystallization from ethanol. The use of this method ensures high purity and selectivity in the product.

Ethyl 1-iodoethyl carbonate (CAS: 80196-04-9) is widely used in the pharmaceutical industry for the synthesis of various drug candidates. It is also used in the polymer industry as a cross-linking agent and in the development of sensors and semiconductors for its unique reactivity and functionality.

When handling Ethyl 1-iodoethyl carbonate (CAS: 80196-04-9), it is crucial to wear appropriate personal protective equipment, including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up immediately using appropriate safety protocols, and the material safety data sheet (MSDS) should always be referenced for detailed safety information.