Ethyl 5-nitro-1-benzofuran-2-carboxylate(CAS: 69604-00-8)

Ethyl 5-nitro-1-benzofuran-2-carboxylate (CAS: 69604-00-8) is a crystalline solid with a molecular weight of approximately 248.15 g/mol. It has a melting point of about 95-97°C and is slightly soluble in water. This compound is known for its reactivity, particularly in nucleophilic substitution and condensation reactions.

Ethyl 5-nitro-1-benzofuran-2-carboxylate (CAS: 69604-00-8) can be synthesized through the nitration of ethyl 1-benzofuran-2-carboxylate followed by purification. This process involves the use of concentrated nitric acid and sulfuric acid as reagents under controlled conditions to achieve high yield and selectivity.

Ethyl 5-nitro-1-benzofuran-2-carboxylate (CAS: 69604-00-8) is primarily used in the pharmaceutical industry due to its structural complexity and potential as a precursor for drug synthesis. It is also of interest in the polymer industry for its ability to enhance material properties.

When handling Ethyl 5-nitro-1-benzofuran-2-carboxylate (CAS: 69604-00-8), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be immediately cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed handling and emergency procedures.