5-(2-Bromophenyl)-1H-tetrazole(CAS: 73096-42-1)

5-(2-Bromophenyl)-1H-tetrazole is a crystalline solid with a molecular weight of approximately 258.03 g/mol. It has poor water solubility but is soluble in organic solvents like dimethyl sulfoxide (DMSO). The compound is known for its stability and low reactivity. It is often used as a building block in organic synthesis due to its functional groups.

5-(2-Bromophenyl)-1H-tetrazole is synthesized by reacting 2-bromoaniline with sodium tetrazole in an aqueous medium. Common solvents include water or DMSO. The reaction is typically carried out at room temperature with good yield and selectivity. The method involves basic conditions and is often performed in a single step.

5-(2-Bromophenyl)-1H-tetrazole is used in the pharmaceutical industry for the synthesis of drug intermediates. It is also utilized in the polymer industry for the production of functional polymers. In addition, it is employed in the development of sensors and semiconductors due to its unique electronic and structural properties.

When handling 5-(2-Bromophenyl)-1H-tetrazole, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid exposure. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.