((2R,3R)-3-(benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl benzoate(CAS: 1173824-58-2)

The compound ((2R,3R)-3-(benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl benzoate has a crystalline form, with a molecular weight of approximately 368.31 g/mol. It is poorly soluble in water but soluble in organic solvents like methanol and acetone. The compound exhibits moderate reactivity, particularly towards nucleophiles and electrophiles. It is used in various chemical reactions due to its functional groups.

((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl benzoate is typically synthesized through a multi-step process involving the protection of a hydroxy group, followed by the introduction of a benzoyloxy group and subsequent fluorination. Common catalysts include aluminum chloride and trifluoromethanesulfonic acid, with a yield of around 70%. The reaction conditions are carefully controlled to ensure high selectivity and purity.

((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl benzoate is used in the pharmaceutical industry for the synthesis of complex organic molecules. It is also utilized in the polymer industry for the development of advanced materials and in the semiconductor industry for electronic applications due to its specific functional groups. Additionally, it has applications in the sensor industry for the development of chemical sensors.

When handling ((2R,3R)-3-(benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl benzoate, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up using appropriate absorbent materials, and disposal should follow local regulations. A safety data sheet (SDS) should be consulted for detailed emergency procedures and handling instructions.