N-(2-Phenylethyl)acetamide(CAS: 877-95-2)

N-(2-Phenylethyl)acetamide (CAS: 877-95-2) is a white crystalline solid with a molecular weight of 168.24 g/mol. It has a pKa of 15.5 and is slightly soluble in water. It is reactive towards nucleophiles and can undergo nucleophilic substitution reactions. It is also soluble in common organic solvents such as ethanol and acetone.

N-(2-Phenylethyl)acetamide (CAS: 877-95-2) can be synthesized by reacting phenylethylamine with acetic anhydride in the presence of an acid catalyst like sulfuric acid. The yield is typically around 85%, and the reaction is exothermic. The product is purified by recrystallization from ethanol.

N-(2-Phenylethyl)acetamide (CAS: 877-95-2) is primarily used in the pharmaceutical industry as a precursor for the synthesis of certain drugs. It is also used in the polymer industry as a stabilizer and in the sensor industry for its ability to interact with specific analytes.

When handling N-(2-Phenylethyl)acetamide (CAS: 877-95-2), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Storage should be in a cool, dry place away from direct sunlight. Fume hoods should be used during handling to minimize inhalation risk. Spills should be cleaned up carefully following standard safety procedures. Always refer to the Safety Data Sheet (SDS) for detailed safety information.