2,2,2-Trifluoro-1-(4-methoxyphenyl)ethanone(CAS: 711-38-6)

2,2,2-Trifluoro-1-(4-methoxyphenyl)ethanone (CAS: 711-38-6) is a colorless to white crystalline solid with a molecular weight of 252.21 g/mol. It has a low solubility in water but is soluble in common organic solvents like dichloromethane, methanol, and acetonitrile. This compound is chemically stable but can react with strong bases. It is not flammable but may release toxic fumes upon decomposition.

2,2,2-Trifluoro-1-(4-methoxyphenyl)ethanone (CAS: 711-38-6) is typically synthesized via a Friedel-Crafts acylation reaction, where 4-methoxybenzoyl chloride reacts with trifluoroacetyl chloride in the presence of aluminum chloride as a catalyst. The reaction is carried out at low temperatures, and the product is obtained with good yield and selectivity.

2,2,2-Trifluoro-1-(4-methoxyphenyl)ethanone (CAS: 711-38-6) is used in the pharmaceutical industry for the synthesis of various drug candidates. It is also utilized in the polymer industry for the development of advanced materials, and in the sensor and semiconductor industries for specific applications requiring high purity and stability.

Proper handling of 2,2,2-Trifluoro-1-(4-methoxyphenyl)ethanone (CAS: 711-38-6) requires wearing appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood. In case of a spill, use appropriate absorbent materials and follow local safety guidelines. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.