Hexyllithium(CAS: 21369-64-2)

Hexyllithium is a colorless to pale yellow liquid with a molecular weight of approximately 103.2 g/mol. It has a high solubility in ether and other organic solvents but is almost insoluble in water. Hexyllithium is highly reactive, readily forming alkyl lithium compounds in the presence of air and moisture.

Hexyllithium is typically synthesized by the reaction of hexyl bromide with lithium metal in an inert solvent like ether under an inert atmosphere. The process involves a substitution reaction where the bromide ion is replaced by a lithium ion, yielding hexyllithium with a high yield and good selectivity.

Hexyllithium is primarily used in the synthesis of organolithium compounds for applications in pharmaceuticals, polymers, and fine chemicals. It is also used in the production of sensors and semiconductors due to its reactivity and ability to form stable organolithium intermediates.

Hexyllithium should be handled in a fume hood and with appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat. It is highly reactive and flammable, so it should be stored in a cool, dry place away from moisture and oxidizers. In case of a spill, use appropriate cleanup materials and refer to the Safety Data Sheet (SDS) for detailed instructions.