2,2',2'',2'''-(1,2-Cyclohexanediyldinitrilo)tetraacetic acid hydrate (1:1)(CAS: 482-54-2)

2,2',2'',2'''-(1,2-Cyclohexanediyldinitrilo)tetraacetic acid hydrate (CAS: 482-54-2) is a crystalline compound with a molecular weight of approximately 528.12 g/mol. It is slightly soluble in water and has a high reactivity towards metal ions. Its physical properties include a melting point of 265-268°C. It is a chelating agent with a high affinity for metal ions, making it useful in various chemical and industrial applications.

2,2',2'',2'''-(1,2-Cyclohexanediyldinitrilo)tetraacetic acid hydrate (CAS: 482-54-2) is typically synthesized through the condensation of 1,2-cyclohexanedionemononitrile with excess ethylenediamine. Commonly, this reaction is carried out under basic conditions using sodium ethoxide as a catalyst. The yield is around 75-85%, and the product is purified by recrystallization from water to obtain the hydrate form.

2,2',2'',2'''-(1,2-Cyclohexanediyldinitrilo)tetraacetic acid hydrate (CAS: 482-54-2) is widely used in the pharmaceutical industry for drug formulation, as a chelating agent to stabilize drugs and enhance their solubility. It is also utilized in the semiconductor industry as a surfactant and in the polymer industry as a stabilizer. Additionally, it finds application in analytical chemistry for metal ion detection and as a reagent in various industrial processes.

When handling 2,2',2'',2'''-(1,2-Cyclohexanediyldinitrilo)tetraacetic acid hydrate (CAS: 482-54-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Ensure to work in a well-ventilated area or fume hood due to its reactivity. Spills should be contained and cleaned up with water, and the area should be flushed with water. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.