3-Chloro-5-methoxypyridine(CAS: 95881-83-7)

3-Chloro-5-methoxypyridine (CAS: 95881-83-7) is a crystalline solid with a molecular weight of approximately 166.58 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophiles. It can undergo substitution reactions and condensation reactions under certain conditions.

3-Chloro-5-methoxypyridine (CAS: 95881-83-7) is typically synthesized via the reaction of 5-methoxypyridine with chlorine gas in the presence of a phase transfer catalyst like tetrabutylammonium chloride. The reaction proceeds with high selectivity and moderate yield, making it a common method in the synthesis of this compound.

3-Chloro-5-methoxypyridine (CAS: 95881-83-7) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the chemical industry for the production of intermediates and in the electronics industry for use in semiconductor materials.

When handling 3-Chloro-5-methoxypyridine (CAS: 95881-83-7), it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up carefully following standard procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.