Compound Q&A

How is 3-Chloro-5-methoxypyridine (CAS: 95881-83-7) typically synthesized?

Answer

3-Chloro-5-methoxypyridine
3-Chloro-5-methoxypyridine (CAS: 95881-83-7) is typically synthesized via the reaction of 5-methoxypyridine with chlorine gas in the presence of a phase transfer catalyst like tetrabutylammonium chloride. The reaction proceeds with high selectivity and moderate yield, making it a common method in the synthesis of this compound.

About

CAS No 95881-83-7
English Name 3-Chloro-5-methoxypyridine
Molecular Formula C6H6ClNO
Molecular Weight 143.57 g/mol
SMILES COC1=CC(=CN=C1)Cl
InChIKey TXBHLLHHHQAFNN-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:38

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