1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile(CAS: 862574-87-6)

1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile is a solid with a crystalline form. Its molecular weight is approximately 265.24 g/mol. It has low water solubility but good solubility in organic solvents. It is moderately reactive, particularly towards nucleophilic substitution reactions. The compound is stable under normal conditions but should be stored in a cool, dark place to prevent degradation.

1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile can be synthesized via a multi-step process involving the preparation of the 2,2-difluoro-1,3-benzodioxol-5-yl intermediate followed by reaction with cyclopropanecarbonitrile. Commonly, this involves the use of palladium catalysts and base conditions, leading to high selectivity and good yield. The reaction is typically conducted under inert atmosphere to prevent side reactions.

1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile is used in pharmaceuticals for its potential as a bioactive compound. It is also utilized in the sensor industry for its ability to interact with certain analytes, and in the semiconductor industry for its potential use in organic electronic devices. Its properties make it a valuable intermediate in the synthesis of other compounds with specific functionalities.

When handling 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile, it is important to use appropriate personal protective equipment (PPE) such as gloves, lab coat, and goggles. The compound should be used in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.