Compound Q&A
How is 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile (CAS: 862574-87-6) typically synthesized?
Answer
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile can be synthesized via a multi-step process involving the preparation of the 2,2-difluoro-1,3-benzodioxol-5-yl intermediate followed by reaction with cyclopropanecarbonitrile. Commonly, this involves the use of palladium catalysts and base conditions, leading to high selectivity and good yield. The reaction is typically conducted under inert atmosphere to prevent side reactions.
About
CAS No
862574-87-6
English Name
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile
Molecular Formula
C11H7F2NO2
Molecular Weight
17.03 g/mol
SMILES
N#CC1(C2=CC=C(OC(F)(F)O3)C3=C2)CC1
InChIKey
RGKFSYDEMAFDQP-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30
