(17beta)-3-Oxoandrost-4-en-17-yl 3-phenylpropanoate(CAS: 1255-49-8)

(17beta)-3-Oxoandrost-4-en-17-yl 3-phenylpropanoate is a colorless to light yellow crystalline solid with a molecular weight of approximately 338.39 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. The compound is relatively stable under normal conditions but can react with strong acids or bases. It is used in pharmaceutical applications and has a melting point of around 80-82°C.

(17beta)-3-Oxoandrost-4-en-17-yl 3-phenylpropanoate can be synthesized through a series of reactions starting from androst-4-ene. The key steps include hydroxylation, alkylation, and acylation. The synthesis typically involves the use of a phase transfer catalyst and requires careful control of pH and temperature to ensure high yield and selectivity. The overall yield is around 70-80%.

(17beta)-3-Oxoandrost-4-en-17-yl 3-phenylpropanoate is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various hormone-related drugs. It is also utilized in the production of certain sensors and semiconductors. Its application in polymers for specific functional properties is less common but still exists.

When handling (17beta)-3-Oxoandrost-4-en-17-yl 3-phenylpropanoate, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight and heat sources. In case of spills, immediately clean up using appropriate absorbent materials and wash the area with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.