1-(4-Hydroxyphenyl)thiourea(CAS: 1520-27-0)

1-(4-Hydroxyphenyl)thiourea is a crystalline compound with a molecular weight of approximately 197.22 g/mol. It has a solubility of about 1.4 g/100 mL in water at 25°C. Chemically, it is reactive towards reducing agents and certain nucleophiles. This compound is used in the preparation of other thiourea derivatives and in some pharmaceutical applications.

1-(4-Hydroxyphenyl)thiourea is typically synthesized via the condensation of 4-hydroxyaniline with thiourea. The reaction is usually carried out in an aqueous medium, with a yield of around 80-85%. Commonly, mild heating and the use of a base catalyst like sodium hydroxide are employed for better selectivity and yield.

1-(4-Hydroxyphenyl)thiourea (CAS: 1520-27-0) is primarily used in the pharmaceutical industry for the preparation of certain drugs. It also finds applications in the polymer industry as a stabilizer and in the production of sensors for detecting various chemical species. In the semiconductor industry, it is used as a precursor in the synthesis of other materials.

When handling 1-(4-Hydroxyphenyl)thiourea (CAS: 1520-27-0), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate safety measures and according to the Material Safety Data Sheet (MSDS). Always consult the SDS for detailed safety information.