2-Bromo-1-methyl-4-nitrobenzene(CAS: 7745-93-9)

2-Bromo-1-methyl-4-nitrobenzene is a crystalline solid with a molecular weight of approximately 222.03 g/mol. It has a density of about 1.38 g/cm³ and is slightly soluble in water. This compound is highly reactive, especially towards nucleophilic substitution and reduction reactions. It is commonly used in the synthesis of dyes, pharmaceuticals, and other organic compounds.

2-Bromo-1-methyl-4-nitrobenzene is typically synthesized through the bromination of 1-methyl-4-nitrobenzene using bromine in the presence of a Lewis acid like aluminum bromide. This process involves the electrophilic aromatic substitution of bromine at the meta position, followed by the introduction of the methyl group. The yield is usually good, and the selectivity is high for this position.

2-Bromo-1-methyl-4-nitrobenzene is used in various industries. It is a key intermediate in the production of dyes, pharmaceuticals, and organic compounds. Specifically, it plays a role in the synthesis of new drugs, dyes for textiles, and materials for electronic and semiconductor applications.

When handling 2-bromo-1-methyl-4-nitrobenzene, it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound is highly reactive and can cause skin irritation and respiratory issues. It should be handled in a well-ventilated fume hood. In case of a spill, immediately clean up using appropriate absorbents and follow the safety data sheet (SDS) guidelines for disposal. For more detailed information, refer to the SDS.