3,5-Bis(trifluoromethyl)benzoyl chloride(CAS: 785-56-8)

CAS Number
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Basic Information
Molecular Formula
C9H3ClF6O
Molecular Weight
276.56 g/mol
Physical Properties
Melting Point
5-10C
Boiling Point
81°C/24mmHg(lit.)
Density
1.526 g/mL at 25 °C(lit.)
Chemical Identifiers
SMILES
C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C(=O)Cl
InChIKey
WAKMMQSMEDJRRI-UHFFFAOYSA-N
Database References
MDL Number
MFCD00000387
Beilstein Registry Number
2593440
FAQ
3,5-Bis(trifluoromethyl)benzoyl chloride (CAS: 785-56-8) is a hazardous chemical classified under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a Category 1A skin corrosion/irritation agent. It is subject to the European Union's Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulations, which require manufacturers and importers to register substances above 1 tonne per year. Additionally, the U.S. Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) have specific guidelines for the handling, storage, and disposal of this compound to ensure worker safety and environmental protection.
While 3,5-Bis(trifluoromethyl)benzoyl chloride (CAS: 785-56-8) is a versatile reagent, alternatives include trifluoromethylbenzoyl chloride itself or other trifluoromethyl-containing reagents such as trifluoromethylbenzoic acid chloride. These alternatives offer similar functional group introduction capabilities but may vary in reactivity and compatibility with specific synthetic routes. It is essential to evaluate the reactivity, solubility, and safety of these alternatives to ensure they meet the desired synthetic objectives.
The market for 3,5-Bis(trifluoromethyl)benzoyl chloride (CAS: 785-56-8) has seen growing demand due to its critical role in the synthesis of pharmaceuticals, agrochemicals, and polymers. Research trends are focusing on the development of more efficient and environmentally friendly synthetic methods, as well as the exploration of new applications in materials science and drug discovery. The increasing focus on trifluoromethylated compounds highlights their importance in modern chemical research and industry.
Waste containing 3,5-Bis(trifluoromethyl)benzoyl chloride (CAS: 785-56-8) should be managed according to local and international regulations. Proper waste collection should involve the use of appropriate containers to prevent leaks or spills. The waste should then be neutralized or treated to reduce the risk of environmental contamination. For safe disposal, consult with a licensed hazardous waste management company. Always follow recommended safety precautions, such as wearing personal protective equipment (PPE) and ensuring proper ventilation during handling and disposal processes.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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