Compound Q&A

Are there alternatives to 3,5-Bis(trifluoromethyl)benzoyl chloride (CAS: 785-56-8) in synthesis?

Answer

3,5-Bis(trifluoromethyl)benzoyl chloride
While 3,5-Bis(trifluoromethyl)benzoyl chloride (CAS: 785-56-8) is a versatile reagent, alternatives include trifluoromethylbenzoyl chloride itself or other trifluoromethyl-containing reagents such as trifluoromethylbenzoic acid chloride. These alternatives offer similar functional group introduction capabilities but may vary in reactivity and compatibility with specific synthetic routes. It is essential to evaluate the reactivity, solubility, and safety of these alternatives to ensure they meet the desired synthetic objectives.

About

CAS No 785-56-8
English Name 3,5-Bis(trifluoromethyl)benzoyl chloride
Molecular Formula C9H3ClF6O
Molecular Weight 276.56 g/mol
SMILES C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C(=O)Cl
InChIKey WAKMMQSMEDJRRI-UHFFFAOYSA-N
Last Updated: 2025-09-23 22:54

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