(R)-1-(Benzyloxy)propan-2-ol(CAS: 89401-28-5)

(R)-1-(Benzyloxy)propan-2-ol (CAS: 89401-28-5) is a colorless liquid with a molecular weight of approximately 202.24 g/mol. It has a melting point of -40°C and a boiling point of 131-132°C. This compound is poorly soluble in water but miscible with ethanol and other organic solvents. Chemically, it is reactive towards elimination and substitution reactions and can be used as a chiral auxiliary in organic synthesis.

(R)-1-(Benzyloxy)propan-2-ol can be synthesized via the reduction of (R)-1-(benzyloxy)propan-2-one using diborane as a reducing agent. The reaction is typically carried out in dichloromethane or other suitable solvents. The yield is around 85-90% with good stereochemical control. This method ensures high purity and selectivity for the desired (R) enantiomer.

(R)-1-(Benzyloxy)propan-2-ol (CAS: 89401-28-5) is primarily used in the pharmaceutical industry as a chiral auxiliary for the synthesis of optically active compounds. It is also employed in polymer science for the preparation of functionalized polymers. The compound's reactivity and chirality make it valuable for applications in sensors and semiconductors where precise chemical reactivity and optical purity are essential.

When handling (R)-1-(Benzyloxy)propan-2-ol (CAS: 89401-28-5), it is important to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be contained and cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions. Disposal of this compound should follow local regulations to prevent environmental contamination.