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N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide(CAS: 77377-52-7)

N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide
CAS Number

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Basic Information

Molecular Formula
C9H18F3NOSi
Molecular Weight
241.33 g/mol

Physical Properties

Boiling Point
170°C(lit.)
Density
1.036 g/mL at 25 °C(lit.)

Chemical Identifiers

SMILES
CC(C)(C)[Si](C)(C)N(C)C(=O)C(F)(F)F
InChIKey
QRKUHYFDBWGLHJ-UHFFFAOYSA-N

Database References

MDL Number
MFCD00009671
Beilstein Registry Number
3606546

FAQ

N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide (CAS: 77377-52-7) falls under the scope of various regulatory guidelines including GHS (Globally Harmonized System of Classification and Labeling of Chemicals) for hazard classification. For EU, it is subject to REACH regulations, which require registration for substances above a certain tonnage. FDA and EPA may have specific requirements related to its use in pharmaceuticals and environmental releases, respectively.
For syntheses requiring similar functionality, alternatives such as trifluoroacetic anhydride or other trifluoroacetamide derivatives can be considered. These alternatives may offer comparable reactivity but with different reaction profiles and handling requirements.
Market trends for N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide (CAS: 77377-52-7) are driven by its application in organic synthesis, particularly in protecting groups and functional group manipulations. Research is exploring its use in medicinal chemistry and materials science, with a focus on improving synthetic methodologies and environmental compatibility.
Waste containing N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide (CAS: 77377-52-7) should be collected in appropriate containers and neutralized if necessary. Professional waste disposal services should be used, especially if the waste contains significant amounts. Proper labeling and documentation are essential to comply with environmental protection regulations.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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