2-Amino-3-(trifluoromethyl)benzoic acid(CAS: 313-12-2)

2-Amino-3-(trifluoromethyl)benzoic acid (CAS: 313-12-2) is a crystalline solid with a molecular weight of approximately 257.09 g/mol. It has a high melting point of around 220-225°C and is slightly soluble in water. This compound is known for its reactivity, particularly in its ability to form salts and esters. Its chemical properties include acidity due to the carboxylic acid group and the presence of a trifluoromethyl group, which influences its reactivity and stability.

2-Amino-3-(trifluoromethyl)benzoic acid (CAS: 313-12-2) can be synthesized through the modification of benzoic acid. One common method involves the trifluoromethylation of benzoic acid followed by the coupling with an amino group. This process requires appropriate catalysts and solvents to ensure selectivity and high yield. The synthesis typically involves the use of trifluoromethylating agents and amino compounds under controlled conditions to achieve the desired product.

2-Amino-3-(trifluoromethyl)benzoic acid (CAS: 313-12-2) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the polymer industry for the production of specialty polymers and in the sensor and semiconductor sectors for specific applications requiring high purity and stability. Its unique chemical properties make it valuable in these specialized fields.

When handling 2-Amino-3-(trifluoromethyl)benzoic acid (CAS: 313-12-2), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or fume hood to prevent inhalation. Spills should be cleaned up immediately with appropriate absorbent materials and proper disposal methods. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.