2-(4-Bromophenyl)-1,3-benzoxazole(CAS: 3164-13-4)

2-(4-Bromophenyl)-1,3-benzoxazole (CAS: 3164-13-4) is a crystalline solid with a molecular weight of approximately 287.03 g/mol. It has a low water solubility and moderate solubility in common organic solvents like ethanol and acetone. Its reactivity is typical for benzoxazole derivatives, showing moderate stability under normal conditions but can undergo substitution reactions under certain conditions.

2-(4-Bromophenyl)-1,3-benzoxazole can be synthesized through a condensation reaction between 4-bromophenol and benzoyl chloride in the presence of a basic catalyst such as pyridine. The reaction is typically carried out at room temperature, yielding a product with a high selectivity and good yield.

2-(4-Bromophenyl)-1,3-benzoxazole is used in various industries. It is an important intermediate in the synthesis of pharmaceuticals, particularly in the development of antiviral and antitumor drugs. It also finds applications in the polymer industry for the production of functional polymers, and in the electronics sector for use in sensors and semiconductors.

When handling 2-(4-Bromophenyl)-1,3-benzoxazole (CAS: 3164-13-4), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or fume hood to minimize exposure. In case of a spill, immediately clean up using appropriate absorbent materials and consult the Safety Data Sheet (SDS) for further instructions on disposal and emergency response.