Trabectedin(CAS: 114899-77-3)

CAS Number
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Basic Information
Molecular Formula
C39H43N3O11S
Molecular Weight
761.85 g/mol
Chemical Identifiers
SMILES
CC1=CC2=C(C3C4C5C6=C(C(=C7C(=C6C(N4C(C(C2)N3C)O)COC(=O)C8(CS5)C9=CC(=C(C=C9CCN8)O)OC)OCO7)C)OC(=O)C)C(=C1OC)O
InChIKey
PKVRCIRHQMSYJX-AIFWHQITSA-N
Database References
MDL Number
MFCD00874849
FAQ
Trabectedin (CAS: 114899-77-3) is subject to regulatory requirements such as REACH in the European Union, which mandates registration, evaluation, authorization, and restriction of chemicals. In the United States, the FDA oversees the approval and safety of Trabectedin, ensuring it meets stringent quality and safety standards. Additionally, EPA regulations may apply for environmental safety considerations.
Alternatives to Trabectedin (CAS: 114899-77-3) in synthesis include various natural and synthetic polyketides and depsipeptides. Isomers and analogs of Trabectedin, such as E7107 and E7430, are also used. Common alternative reagents in the synthesis of similar compounds include various alcohols, acids, and amides, providing flexibility for chemical synthesis.
The market for Trabectedin (CAS: 114899-77-3) is primarily driven by its use in oncology, particularly for the treatment of soft tissue sarcomas and ovarian cancer. Research trends focus on understanding its mechanisms of action and exploring its potential for combination therapies. Additionally, there is ongoing research to develop derivatives and analogs that may improve efficacy and reduce side effects.
Waste containing Trabectedin (CAS: 114899-77-3) should be collected in appropriate containers and stored in a secure, well-ventilated area until disposal. Incineration is a common method for disposal, although professional waste disposal services are recommended. Environmental protection precautions include ensuring no contaminants enter water systems and following local hazardous waste regulations.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
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