Phenylmethanesulfonyl fluoride(CAS: 329-98-6)

Phenylmethanesulfonyl fluoride (PMSF), with the CAS number 329-98-6, is an organic compound commonly used as a serine protease inhibitor. It has the chemical formula C8H9FO2S and appears as a white crystalline solid. PMSF is known for its reactivity and ability to inhibit enzymes by forming covalent bonds with the active site's serine residue.

Phenylmethanesulfonyl fluoride (PMSF) is widely used in pharmaceutical research, biochemistry, and protein analysis. It serves as a tool to study enzyme activity and is applied in drug development, particularly in the inhibition of proteolytic enzymes. PMSF is also used in the purification of proteins and in the synthesis of various organic compounds.

Phenylmethanesulfonyl fluoride (PMSF) is considered toxic and should be handled with care. It can cause irritation to the skin, eyes, and respiratory system, and may be harmful if ingested. Safety protocols include using personal protective equipment (PPE) and working in a well-ventilated area. It is not recommended for use in food or consumer products due to its chemical nature.

Phenylmethanesulfonyl fluoride (PMSF) should be stored in a cool, dry, and dark place, ideally at temperatures below 25°C. It is sensitive to moisture and light, so it must be kept in a sealed, airtight container. Proper storage ensures stability and prevents degradation of the compound's activity.