5-Methyl-2-thiophenecarbaldehyde(CAS: 13679-70-4)

5-Methyl-2-thiophenecarbaldehyde (CAS: 13679-70-4) is a colorless to light yellow liquid with a molecular weight of approximately 146.19 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. It is moderately reactive, particularly towards nucleophiles and can undergo condensation reactions. It crystallizes in the monoclinic system.

5-Methyl-2-thiophenecarbaldehyde can be synthesized via the reaction of 2-thiophenecarbonyl chloride with methylamine. This process yields the target compound in a moderate yield of around 70%. The use of a phase transfer catalyst can improve the reaction efficiency and selectivity.

5-Methyl-2-thiophenecarbaldehyde finds applications in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also used in the polymer industry for the preparation of specific types of polymers. Additionally, it is utilized in the development of chemical sensors and as a precursor in semiconductor manufacturing processes.

When handling 5-Methyl-2-thiophenecarbaldehyde (CAS: 13679-70-4), it is important to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. It should be stored in a cool, well-ventilated area away from heat and open flames. In case of spillage, it should be absorbed with an appropriate non-combustible material and disposed of according to local hazardous waste regulations. Always refer to the Safety Data Sheet (SDS) for detailed information and emergency procedures.