Diethyl bromomalonate(CAS: 685-87-0)

Diethyl bromomalonate (CAS: 685-87-0) is a colorless to light yellow liquid with a molecular weight of 183.04 g/mol. It has a density of approximately 1.18 g/cm³ and a melting point of -50.0°C. This compound is moderately soluble in water but is highly soluble in organic solvents. It is known for its reactivity in nucleophilic substitution reactions due to the presence of the bromide ion.

Diethyl bromomalonate (CAS: 685-87-0) is typically synthesized from malonic acid and bromine in the presence of an alkali metal bromide catalyst. The reaction involves the bromination of malonic acid, followed by the addition of diethyl ether. This method provides a high yield and good selectivity for the desired product.

Diethyl bromomalonate (CAS: 685-87-0) is used in various industries, including pharmaceuticals for intermediate synthesis, as a starting material in polymer chemistry for the production of specific polymers, and in sensor technology for detecting specific chemical compounds. Its versatility and reactivity make it valuable in these sectors.

When handling Diethyl bromomalonate (CAS: 685-87-0), it is important to use appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be stored in a cool, dry place away from heat sources and incompatible materials. Fume hoods should be used during handling to minimize inhalation risk. In case of spills, neutralize with an appropriate reagent before disposal. Always refer to the Safety Data Sheet (SDS) for detailed safety information.