(2,6-Dichlorophenyl)boronic acid(CAS: 73852-17-2)

(2,6-Dichlorophenyl)boronic acid is a white crystalline solid with a molecular weight of approximately 231.03 g/mol. It has a solubility of about 30 mg/L in water. Chemically, it is less reactive than phenylboronic acid due to the electron-withdrawing effect of the chlorine groups. It is an important reagent in organic synthesis, particularly in Suzuki coupling reactions.

(2,6-Dichlorophenyl)boronic acid is commonly synthesized via the reaction of 2,6-dichlorophenol with sodium borohydride. The synthesis involves mild conditions and is known for its high yield and good selectivity. The process is often conducted in aqueous media and requires careful temperature control to avoid decomposition.

(2,6-Dichlorophenyl)boronic acid is widely used in the pharmaceutical industry for the synthesis of complex organic molecules. It also finds application in the polymer industry, particularly in the preparation of functionalized polymers. Its use in sensors and semiconductors is also growing due to its reactivity and stability.

Handling (2,6-Dichlorophenyl)boronic acid should be done in a well-ventilated area with the use of personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be handled with care to avoid skin and eye contact. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions.