4-Pyridinylmethanol(CAS: 586-95-8)

4-Pyridinylmethanol (CAS: 586-95-8) is a colorless to slightly yellow liquid with a molecular weight of 119.13 g/mol. It has a pKa of 12.9 and a boiling point of 253°C. The compound is poorly soluble in water but soluble in ethanol and chloroform. It is moderately reactive, particularly with acids and bases, and can undergo typical alcohol reactions such as esterification and alkylation.

4-Pyridinylmethanol is typically synthesized by reducing 4-pyridinemethanone with sodium borohydride. The key steps involve the reduction of the ketone functional group to form the alcohol. This process yields good selectivity and moderate to high yield, depending on the reaction conditions and catalysts used.

4-Pyridinylmethanol (CAS: 586-95-8) is used in various industries, including pharmaceuticals, where it serves as a precursor to drug synthesis, and in the chemical synthesis of polymers and sensors. Its functionality as an alcohol makes it useful in developing materials with specific reactivity and solubility properties.

Proper safety measures should be taken when handling 4-Pyridinylmethanol (CAS: 586-95-8) due to its reactivity and potential health risks. Use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation. Store in a cool, dry place away from heat sources. In case of spill, refer to the safety data sheet (SDS) for appropriate cleanup procedures.