3'-Azido-3'-deoxythymidine(CAS: 30516-87-1)

CAS Number
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Basic Information
Molecular Formula
C10H13N5O4
Molecular Weight
267.24 g/mol
Physical State
Powder
Physical Properties
Melting Point
113-115 °C (lit.)
Boiling Point
410.43°C (rough estimate)
Flash Point
9℃
Water Solubility
1-5 g/100 mL at 17 ºC
Chemical Identifiers
SMILES
CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]
InChIKey
HBOMLICNUCNMMY-XLPZGREQSA-N
Database References
MDL Number
MFCD00386763
Beilstein Registry Number
3595791
FAQ
3'-Azido-3'-deoxythymidine, also known as AZT, is an antiretroviral compound used in the treatment of HIV. Its chemical formula is C14H14N4O3. It is a white crystalline solid that is soluble in water and has a molecular weight of 266.29 g/mol. This compound is a nucleoside analog that inhibits the enzyme reverse transcriptase, which is essential for HIV replication.
3'-Azido-3'-deoxythymidine (AZT) is primarily used in pharmaceuticals as an antiretroviral drug for managing HIV infections. It is also employed in research for studying antiviral mechanisms and in the development of new therapeutic agents. Additionally, it has applications in molecular biology for nucleic acid synthesis and as a tool in drug discovery processes.
3'-Azido-3'-deoxythymidine (AZT) is generally considered safe when used as prescribed in medical treatment, but it can have side effects such as bone marrow suppression and liver toxicity. Proper handling and adherence to safety guidelines are essential. It is classified as a Schedule II controlled substance in some regions due to its potential for abuse and the need for strict regulatory control.
3'-Azido-3'-deoxythymidine (AZT) should be stored in a cool, dry place away from direct light. It is typically kept in airtight containers to prevent moisture absorption. Stability is maintained under these conditions, and it is important to store it properly to ensure its efficacy and safety. Always follow manufacturer guidelines for specific storage requirements.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures





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