1,3-Phenylenediboronic acid(CAS: 4612-28-6)

1,3-Phenylenediboronic acid is a boronic acid derivative with the CAS number 4612-28-6. It is a white solid with a molecular formula of C8H8BO3. This compound has a pKa of approximately 7.5 and is soluble in water and organic solvents. It is known for its reactivity towards diols and its applications in organic synthesis, particularly in Suzuki coupling reactions.

1,3-Phenylenediboronic acid is primarily used in organic synthesis, particularly for Suzuki coupling reactions, which are widely employed in the pharmaceutical and agrochemical industries for the preparation of heterocycles and biologically active compounds. It is also used in the preparation of boronic esters and as a reagent in multistep organic transformations.

1,3-Phenylenediboronic acid is generally considered safe for laboratory use when handled with proper precautions. However, it is important to follow safety guidelines, such as wearing appropriate personal protective equipment (PPE) including gloves and goggles. This compound is not flammable but should be stored in a cool, dry place away from direct sunlight and heat sources to prevent degradation.

1,3-Phenylenediboronic acid should be stored in a cool, dry place away from direct sunlight and heat sources to maintain its stability. Protect it from moisture and store it in a tightly sealed container to prevent degradation. It is recommended to store it at a temperature range of 15-25°C (59-77°F) to ensure optimal conditions for long-term storage and reactivity.