8-Anilino-8-oxooctanoic acid(CAS: 149648-52-2)

8-Anilino-8-oxooctanoic acid (CAS: 149648-52-2) is a crystalline solid with a molecular weight of approximately 218.21 g/mol. It is slightly soluble in water and more soluble in organic solvents. The acid is moderately reactive, particularly towards bases, and can undergo esterification and amidation reactions. It has a melting point of around 205-207°C.

8-Anilino-8-oxooctanoic acid is typically synthesized by the condensation of anilino-8-oxooctanoic acid chloride with ammonia. The reaction is conducted under anhydrous conditions using a catalyst such as anhydrous aluminum chloride. The yield is around 80-85%, and the product is purified by recrystallization.

8-Anilino-8-oxooctanoic acid (CAS: 149648-52-2) is used in various industries. It serves as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antiviral and antifungal drugs. It is also utilized in the production of sensors for detecting nitrogen oxides and in the manufacturing of certain polymers and semiconductors.

When handling 8-Anilino-8-oxooctanoic acid (CAS: 149648-52-2), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store the compound in a well-ventilated area and use a fume hood during operations. In case of a spill, immediately evacuate the area and follow the emergency procedures outlined in the safety data sheet (SDS).