5-bromo-4-fluoro-pyridin-2-amine(CAS: 944401-69-8)

5-Bromo-4-fluoro-pyridin-2-amine (CAS: 944401-69-8) is a solid with a crystalline form. It has a molecular weight of approximately 240.03 g/mol. This compound is moderately soluble in water and soluble in organic solvents like dichloromethane and ethanol. It is slightly reactive, showing basic properties due to the amine group. It can be used in various synthetic reactions, typically requiring mild to moderate conditions.

5-Bromo-4-fluoro-pyridin-2-amine (CAS: 944401-69-8) is often synthesized through a multi-step process involving the bromination of 4-fluoropyridine followed by an amination step. The synthesis typically requires the use of a brominating agent, such as N-bromosuccinimide (NBS), and a suitable amine. The process yields a high purity product with good selectivity. The overall yield is generally around 70-80%.

5-Bromo-4-fluoro-pyridin-2-amine (CAS: 944401-69-8) is primarily used in the pharmaceutical and chemical industries. It serves as a precursor in the development of new drugs and as an intermediate in the synthesis of various chemical compounds. Its properties make it useful in the production of polymers, sensors, and semiconductors, although its application in these areas is less common compared to pharmaceuticals.

When handling 5-bromo-4-fluoro-pyridin-2-amine (CAS: 944401-69-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to minimize exposure to the potentially harmful vapor. Spills should be handled with caution, using appropriate cleanup procedures and ensuring that all waste is disposed of in compliance with local regulations. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage.