1-(3-Bromo-4-methoxyphenyl)ethanone(CAS: 35310-75-9)

1-(3-Bromo-4-methoxyphenyl)ethanone (CAS: 35310-75-9) is a white crystalline solid with a molecular weight of approximately 255.02 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetonitrile. This compound is known for its moderate reactivity, particularly towards nucleophilic substitution reactions at the bromine atom. It is also susceptible to hydrolysis under basic conditions.

1-(3-Bromo-4-methoxyphenyl)ethanone (CAS: 35310-75-9) is typically synthesized through the reaction of 4-methoxyphenylacetic acid with bromine in the presence of a Lewis acid catalyst such as aluminum bromide. The reaction involves bromination of the phenyl ring followed by elimination to form the ketone. The yield is generally good, around 80-90%, and the reaction is selective towards the bromination of the meta-position.

1-(3-Bromo-4-methoxyphenyl)ethanone (CAS: 35310-75-9) is used in various industries including pharmaceuticals, where it serves as an intermediate in drug synthesis. It is also utilized in the synthesis of certain materials for polymers and sensors. Additionally, this compound has potential applications in the development of semiconductors due to its electronic properties.

When handling 1-(3-Bromo-4-methoxyphenyl)ethanone (CAS: 35310-75-9), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. Spills should be cleaned up using absorbent material and disposed of according to local regulations. Consulting the Safety Data Sheet (SDS) for detailed handling and safety information is recommended.