Dimethyl ethylmalonate(CAS: 26717-67-9)

Dimethyl ethylmalonate (CAS: 26717-67-9) is a colorless liquid with a molecular weight of approximately 164.14 g/mol. It has a characteristic odor and is slightly soluble in water but miscible with most organic solvents. The compound is reactive towards nucleophiles and can undergo esterification and hydrolysis reactions. It crystallizes in the orthorhombic system, forming prismatic crystals.

Dimethyl ethylmalonate (CAS: 26717-67-9) is commonly synthesized via the esterification of ethylmalonic acid with dimethyl carbonate in the presence of a strong acid catalyst such as sulfuric acid. The reaction is performed at high temperatures to achieve high yields and selectivity, with the product being purified by distillation or recrystallization.

Dimethyl ethylmalonate (CAS: 26717-67-9) finds applications in various industries, including pharmaceuticals, where it serves as a precursor in the synthesis of certain drugs. It is also used in the production of polymers, as a chemical intermediate, and in the development of sensors and semiconductors due to its reactivity and functional groups.

Precautions for handling Dimethyl ethylmalonate (CAS: 26717-67-9) include the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents, and the area should be flushed with water. It is essential to always refer to the Safety Data Sheet (SDS) for detailed handling and safety guidelines.